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KMID : 1189320200140030312
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Asian Spine Journal
2020 Volume.14 No. 3 p.312 ~ p.319
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Evaluating Spinal Canal Lesions Using Apparent Diffusion Coefficient Maps with Diffusion-Weighted Imaging
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Kanamoto Hirohito
Norimoto Masaki
Eguchi Yawara
Oikawa Yasuhiro
Orita Sumihisa
Inage Kazuhide
Abe Koki
Inoue Masahiro
Kinoshita Hideyuki
Umimura Tomotaka
Matsumoto Koji
Masuda Yoshitada
Furuya Takeo
Koda Masao
Aoki Yasuchika
Watanabe Atsuya
Takahashi Kazuhisa
Ohtori Seiji
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Abstract
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Study Design: Observational study.
Purpose: To evaluate healthy volunteers and patients with spinal canal lesions using apparent diffusion coefficient (ADC) maps with diffusion-weighted imaging.
Overview of Literature: Decompression surgery for lumbar spinal stenosis (LSS) is selected on the basis of subjective assessment and cross-sectional magnetic resonance imaging (MRI). However, there is no objective standard for this procedure.
Methods: We performed 3T MRI in 10 healthy volunteers and 13 patients with LSS. The ADC values in the spinal canal were evaluated at 46 vertebrae (L4/5 and L5/S1 for each participant), and the reduced and conventional fields of view were compared.
Results: The ADC values were 2.72±0.12 at L4/5 in healthy volunteers, 2.76±0.19 at L5/S1 in healthy volunteers, 1.77±0.58 at L4/5 in patients with LSS, and 2.35±0.29 at L5/S1 in patients with LSS. The ADC value at L4/5 in patients with LSS was significantly lower than that at L5/S1 in patients with LSS and that at L4/5 and L5/S1 in healthy volunteers (p <0.05). With an ADC cutoff value of 2.46 to identify LSS, this approach provided an area under the curve of 0.81, sensitivity of 0.92, and specificity of 0.76 (p <0.05).
Conclusions: Preoperative examination using ADC maps permits visualization and quantification of spinal canal lesions, thus proving the utility of ADC maps in the selection of decompression surgery for LSS.
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KEYWORD
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Spinal canal lesions, Diffusion-weighted imaging, Apparent diffusion coefficient map, Decompression surgery
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